Lei Fang, George Karakiulakis, Michael Roth
Published:March 11, 2020
… These data suggest that ACE2 expression is increased in diabetes and treatment with ACE inhibitors and ARBs increases ACE2 expression. Consequently, the increased expression of ACE2 would facilitate infection with COVID-19. We therefore hypothesise that diabetes and hypertension treatment with ACE2-stimulating drugs increases the risk of developing severe and fatal COVID-19.
The Lancet – DOI: https://doi.org/10.1016/S2213-2600(20)30116-8